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| We were delighted to participate in WC12 in Niagara Falls and Eurotox in Ljubljana during the past summer, where our team and partners delivered several posters and presentations. |
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This year's scientific theme brought attention to the non-animal GARD® sensitization assay and explored various aspects, including Difficult-to-Test, Quantitative Potency and Medical Devices.
Furthermore, our Group company ToxHub provided an in-depth exploration of E&L Assessment in their poster on mitigating risks in pharmaceutical applications. |
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In a recent quantitative risk assessment project by IFF and RIFM, GARD®skin Dose-Response was considered to provide useful information for continuous predictions of skin sensitizing potency. The results demonstrate that the LLNA EC3 values and the human NESIL values predicted from the GARD®skin Dose-Response assay are reproducible between experiments and show good concordance with the published NESIL and EC3 values.
Together with the reported performance data, this represents a major step towards the establishment of the assay as a relevant source of information to derive NESIL values for conducting QRA evaluations for fragrance materials to ensure product safety while avoiding the generation of new animal data.
For more details, request a copy of the poster. |
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🎧 Webinar: Latest GARD® innovation & research in in vitro skin sensitization | Oct 18 🌎 Conference: ACT | Orlando, Florida | Nov 12-15 🌎 Conference: Annual Medical Device Biocompatibility Conference | Berlin | Nov 17 🌎 Conference: CFIC | Lyon, France | Nov 21-22 |
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